Now we know there is no cure for cancer, even for our furry friends, but CBD is coming pretty darn close. This is the story of Barney, a 6 year old German Hair Pointer male. Before cancer Barney was the most energetic pup, so much so that he almost had too much energy. A lover of chasing squirrels and racing birds, Barney maintained a lean frame throughout his early adult life averaging about 55 lbs give or take. According to his owners, Barney's health has always been good - aside from his over activity. One day in early September though, Barney stopped eating completely. He had just been to the vet not more than a month before but in that short time frame, his family learned he had developed rapid lymphoma cancer and it had spread. Over the next few weeks Barney's weight dropped dramatically as his family tried everything to get him to eat. At just 29lbs he was too weak to take on chemotherapy. But then they turned to CBD and reached out to Green Drop for direction on what products to use or dose to give. Barney was put on a regime of 75mg CBD twice a day, using a flavorless tincture of 1500 mg potency. Almost immediately Barney's appetite came back. After just a few days on CBD he was able to gain enough strength and weight to start chemotherapy shots. Now at 48lbs, Barney has been able to go through 4 sessions of chemotherapy. Although his lymphoma is still very prevalent, the growth of the cancer cells has slowed and Barney has been able to stay off of steroids. Our hopes and prayers are with this little fighter and his family!
Barney at 29lbs days after diagnosis
Barney at 48lbs 3 weeks after starting CBD and chemotherapy
Cannabinoids, the molecular family in which CBD belongs, work by binding to certain cell receptors that make up the human endocannabinoid system. These are the CB1 and CB2 receptors. Interestingly, it's been noted by researchers that CBD induced its anticancer effects independent of the
“Many cannabinoids mediate their effects by binding to CB1, CB2, or the vallinoid receptor (3, 4); however, our results indicate that CBD induces PCD independent of these receptors. This is a promising area for future investigation in that identifying the receptor through which CBD mediates its anticancer effects may better inform the design of novel drugs with a mechanism of action similar to CBD.
“In this study we showed that CBD induced both apoptosis and autophagy-induced death in breast cancer cells. PCD by apoptosis is well-documented, whereas autophagy-mediated cell death is a relatively recent discovery, and there is much to be learned about the factors that prejudice autophagy toward self-protection or self-destruction.”
As more and more research is being done on CBD and it's incredible health benefits, the general understanding of cannabinoids full potential is also improving.
Even the American Cancer Society is promoting Marijuana and CBD for it's potential benefits and impact on cancer and other symptoms related to cancer treatment.
"More recently, scientists reported that THC and other cannabinoids such as CBD slow growth and/or cause death in certain types of cancer cells growing in lab dishes. Some animal studies also suggest certain cannabinoids may slow growth and reduce spread of some forms of cancer.
There have been some early clinical trials of cannabinoids in treating cancer in humans and more studies are planned. While the studies so far have shown that cannabinoids can be safe in treating cancer, they do not show that they help control or cure the disease." American Cancer Society